en عمومى General پژوهشي Research <p><strong>Background</strong>:<em> Stachys</em> (Lamiaceae) is a genus with varied effects and applications in traditional medicine. The essential oil (EO) of different species of genus <em>Stachys</em> has received much attention in different studies. According to previous evidence, the components of EO in different species have diversity although there is no previous data regarding investigating <em>Stachys fruticulosa</em> for EO. Considering the importance of the plants of genus <em>Stachys</em>, vast types of compounds in the EO of the genus, the aim of the present study was to evaluate the components of EO of <em>S. fruticulosa</em> M. Bieb.</p> <p><strong>Methods</strong>: The EO of the aerial parts from <em>S. fruticulosa</em> was obtained by hydrodistillation and then the oil was analyzed by gas chromatography/mass spectrometry (GC/MS) and 95% of the oil (17 components) was identified accordingly. The identity of the components was assigned by comparing their mass spectra and retention indices with those of authentic samples.</p> <p><strong>Results</strong>: Most oil components were &alpha;-terpinyl acetate (24.6%), 3-n-Butyl phthalide (20.5%),<em> p</em>-cymene (18.2%), and &beta;-phellandrene (18.2%).</p> <p><strong>Conclusion</strong>: The components of essential oil from <em>S. fruticulosa</em> were identified for the first time, and these substances may be responsible for the biological effects of these essential oils.</p> Stachys fruticulosa, Lamiaceae, Essential oil, GC-MS 33 36 http://ajpr1.umsha.ac.ir/browse.php?a_code=A-10-2-28&slc_lang=en&sid=1 Faraz Mojab sfmojb@sbmu. ac.ir 1003194753284600167 1003194753284600167 Yes School of Pharmacy and Pharmaceutical Sciences Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Neda Khalaj 1003194753284600168 1003194753284600168 No Khalaj